Ø Teachers:
Daniel Kling (daniel.kling@rmv.se)
and Andreas Tillmar (andreas.tillmar@rmv.se)
Brief description
The aim of this workshop is to give a
comprehensive introduction to X-chromosomal
markers in forensic genetics with a focus on kinship applications. The workshop
is divided into three session, i) Basic where we
introduce concepts such as the likelihood ratio principle and how underlying
theory for calculations, ii) Advanced where we continue with concepts such as
linkage and linkage disequilibrium and iii) Applications and examples where we
showcase interesting cases. Theoretical presentations will be mixed with
hands-on exercises.
Statistical methods are introduced and the freely available
software FamLinkX is exemplified. The open software R
is introduced, and the relevance for plotting of pedigrees and estimation of
haplotype frequencies is demonstrated.
Lectures will be in English.
Preparation
Participants should bring
their own laptop if possible. Users are encouraged to download and install
the biostatistical software R, any version,
as well as FamLinkX
(version 2.9.3) which may be used in exercises.
General
information
Workshop
Time & Date: 16:00-19:00 (CET), March 10, 17 and 24, 2025
Preliminary schedule (subject
to changes)
Session
1 – Basics (March 10)
16:00 Introduction
16:15-17:00 Basics
of kinship testing and the utility of X-chromosomal markers
17:00-17:10 Short break
17:10-18:00 Software: FamLinkX
18:05-18:40 Theory and hands-on: Exercises
and Solutions
FamLinkX:
Exercises
and Solutions
and Files
18:40-19:00 Summary
Session
2 – Advanced (March 17)
16:00 Introduction (Question and
Answers)
16:15-17:00 Advanced theory
17:00-17:10 Short break
17:10-18:00 Haplotypes
and databases
18:05-18:40 Exercises (see Session 1 links)
18:40-19:00 Summary
Session
3 – Applications and examples (March 24)
16:00 Introduction (Question and
Answers)
16:15-17:00 Summary of
theory and some more advanced topics
17:00-17:10 Short break
17:10-18:00 Case
examples and more advanced topics
18:05-18:40 Exercises (see Session 1 links)
18:40-19:00 Summary