Ø Teachers: Daniel Kling (daniel.kling@rmv.se)
and Andreas Tillmar (andreas.tillmar@rmv.se)
Brief description
The aim of this workshop is to give a
comprehensive introduction to X-chromosomal
markers in forensic genetics with a focus on kinship applications. The workshop
is divided into three session, i) Basic where we introduce concepts such as the
likelihood ratio principle and how underlying theory for calculations, ii)
Advanced where we continue with concepts such as linkage and linkage
disequilibrium and iii) Applications and examples where we showcase interesting
cases. Theoretical presentations will be mixed with hands-on exercises.
Statistical methods are introduced and the freely available
software FamLinkX is exemplified. The open software R is introduced, and the
relevance for plotting of pedigrees and estimation of haplotype frequencies is
demonstrated.
Lectures will be in English.
Preparation
Participants should bring
their own laptop if possible. Users are encouraged to download and install
the biostatistical software R, any version, as well as FamLinkX (version 2.1) which may
be used in exercises.
General
information
Workshop
Time & Date: 16:00-19:00 (CET), March 10, 17 and 24, 2025
Preliminary schedule (subject
to changes)
Session
1 – Basics (March 10)
16:00 Introduction
16:15-17:00 Basics of kinship testing
17:00-17:10 Short break
17:10-18:00 Utility of X-chromosomal markers
18:05-18:40 Exercises
18:40-19:00 Summary
Session
2 – Advanced (March 17)
16:00 Introduction
16:15-17:00 Advanced theory
17:00-17:10 Short break
17:10-18:00 Haplotypes
and databases
18:05-18:40 Exercises
18:40-19:00 Summary
Session
3 – Applications and examples (March 24)
16:00 Introduction
16:15-17:00 Summary of theory and some more advanced
topics
17:00-17:10 Short break
17:10-18:00 Examples
18:05-18:40 Exercises
18:40-19:00 Summary